EconomyMarkets

AstraZeneca starts trial of COVID-19 antibody treatment By Reuters

2/2
© Reuters. FILE PHOTO: A sign at an AstraZeneca site in Macclesfield

2/2

By Pushkala Aripaka and Aakash B

(Reuters) – British drugmaker AstraZeneca (NYSE:) has begun testing an antibody-based cocktail for the prevention and treatment of COVID-19, adding to recent signs of progress on possible medical solutions to the disease caused by the novel coronavirus.

The London-listed firm, already among the leading players in the global race to develop a successful vaccine, said the study would evaluate if AZD7442, a combination of two monoclonal antibodies (mAbs), was safe and tolerable in up to 48 healthy participants between the ages of 18 and 55 years.

If the UK-based early-stage trial, which has dosed its participants, shows AZD7442 is safe, AstraZeneca said it would proceed to test it as both a preventative treatment for COVID-19 and a medicine for patients who have it, in larger, mid-to-late-stage studies.

AstraZeneca shares were up about 1% at 87 pounds ($114) in early trading.

Development of mAbs to target the virus, an approach already being tested by Regeneron (NASDAQ:), ELi Lilly, Roche and Molecular Partners, has been endorsed by leading scientists.

mAbs mimic natural antibodies generated in the body to fight off infection and can be synthesised in the laboratory to treat diseases in patients. Current uses include treatment of some types of cancers.

U.S. infectious diseases expert Anthony Fauci has called them “almost a sure bet” against COVID-19, and AstraZeneca in June received $23.7 million in funding from U.S. government agencies to advance development of antibody-based treatments for COVID-19.

“This combination of antibodies, coupled to our proprietary half-life extension technology, has the potential to improve both the effectiveness and durability of use in addition to reducing the likelihood of viral resistance,” said Astra’s executive vice president of biopharmaceuticals R&D Mene Pangalos.

Though vaccines are at the heart of the long-term fight against the pandemic, alternative treatments are also being advanced, and the United States on Sunday authorized use of recovered COVID-19 patients’ plasma to treat those who are ill.

The Financial Times reported at the weekend that President Donald Trump’s administration was considering a fast-tracked approval of AstraZeneca’s COVID-19 vaccine before November’s elections.

Disclaimer: Fusion Media would like to remind you that the data contained in this website is not necessarily real-time nor accurate. All CFDs (stocks, indexes, futures) and Forex prices are not provided by exchanges but rather by market makers, and so prices may not be accurate and may differ from the actual market price, meaning prices are indicative and not appropriate for trading purposes. Therefore Fusion Media doesn`t bear any responsibility for any trading losses you might incur as a result of using this data.

Fusion Media or anyone involved with Fusion Media will not accept any liability for loss or damage as a result of reliance on the information including data, quotes, charts and buy/sell signals contained within this website. Please be fully informed regarding the risks and costs associated with trading the financial markets, it is one of the riskiest investment forms possible.


Source link

Show More

Related Articles

Leave a Reply

Your email address will not be published. Required fields are marked *

Back to top button